Waterborne Exophiala species causing disease in cold-blooded animals

Waterborne Exophiala species causing disease in cold-blooded animals

The majority of mesophilic waterborne species of the black yeast genus Exophiala (Chaetothyriales) belong to a single clade judging from SSU rDNA data. Most taxa are also found to cause cutaneous or disseminated infections in cold-blooded, water animals, occasionally reaching epidemic proportions. Hosts are mainly fish, frogs, toads, turtles or crabs, all sharing smooth, moist or mucous skins a...

Oxygen Poisoning in Cold Blooded Animals

1. Exposure of frogs to atmospheres containing approximately 95 per cent of oxygen is without apparent effect on their state of well being, and produces no noticeable changes in the appearance of their web capillaries. 2. Turtles exposed to similar atmospheres are also apparently unaffected unless the oxygen be warmed to mammalian temperature. 3. At this temperature (37.5 degrees C.) the turtle...

The Behavior of Bacillus Lepræ in Cold-blooded Animals

Before proceeding to a discussion of the experiments upon cold-blooded animals, it is necessary to review briefly some of the work recently done with the bacillus of leprosy. The appearance of the bacillus in man and its behavior under artificial cultivation, and in the tissues of lower animals, should be considered in order that comparisons may be drawn. In their studies with the organism unde...

A Unique Bacterium Pathogenic for Warm-blooded and Cold-blooded Animals

In vitro activities of eight antifungal drugs against 106 waterborne and cutaneous exophiala species.

The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.25 μg/ml; micafungin, 1 μg/ml; voriconazole, 2 μg/ml; isavuconazole, 4 μ...